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After incubation with a horseradish peroxidase (HRP)-conjugated anti-mouse (W4021) or anti-rabbit (W4011) antibody (Promega, Fitchburg, WI), the immunoreactive bands were visualised using an enhanced chemiluminescence kit (BD Biosciences, Franklin Lakes, NJ) and imaged with an ImageQuant LAS-4000 system (GE Healthcare, Chicago, IL)

Recently, a non-operative treatment option has become available for patients with an excellent response to chemotherapy

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It is important to note that smoking is harmful to health, not only affects the heart, lungs but also causes dental diseases (periodontitis, heavy tartar, tongue inflammation, bad breath ), especially to mention the risk of dental implants failure