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Medical providers sometimes perceive lighter smokers as not addicted and, therefore, not in need of treatment, but this study suggests many of them may have significant difficulty quitting without assistance. The researchers examined an existing data set from the National Institutes of Health, including more than 6,700 smokers who had been fully assessed to find out if they met the DSM-5 criteria for tobacco use disorder

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figure 10) is described as an advancing form of leukoplakia that starts as a flat, hyperkeratotic white patch and progresses to a verrucous or papillary form and then finally to invasive squamous cell carcinoma