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[2] By 1920, around half of states had their minimum purchase age of 21 and some simply prohibited "minors" (ages 1424) from purchasing

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45 The findings that dual users of cigarettes and e-cigarettes have worse HRQoL than 5-year cessation may reflect the fact that these persons tend to be heavier, more dependent smokers 46 compared to 5-year cessation, many of whom may not have been heavy cigarette smokers to begin with

Others swear by THC-dominant flower for pain or sleep, but lean on CBD during the day to stay functional