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Only one cross-sectional study reported that non-smoker current vapers had faster lung aging than never smokers, and the effect was similar to that seen among non-vaper current smokers, suggesting that non-smoker current vapers had an increased risk of age-related lung disease, including cancer 32

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Microorganisms and endotoxin cross the intestinal mucosal barrier into the blood and induce endotoxemia, subsequently leading to injury to the liver and other organs, intestinal inflammation, and rectal carcinogenesis (Elamin et al., 2013)