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Biological factors involve neurochemical changes, physical dependence, and genetic susceptibility

15 Nortriptyline is contraindicated in the immediate recovery period following myocardial infarction, in patients with pre-existing arrhythmias (particularly heart block), during manic episodes of bipolar disorder and within 14 days of monoamine oxidase inhibitor use

The rising burden of smoking-related bladder cancer in the US may be attributed to several interrelated factors

Prohibition, enacted in 1920, was a well-intentioned failure aimed at shielding Americans from the scourge of drunkenness and quickly became a cautionary tale of unintended consequences