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This design was selected because the estimate of within-arm standard deviation (SD) from the external pilot study had a wide confidence interval and the interim analysis would allow for a more accurate estimation of the SD as a basis for assessing whether the expected effect size could be feasibly demonstrated

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We intend to clear the market of flavored e-cigarettes to reverse the deeply concerning epidemic of youth e-cigarette use, Health and Human Services Secretary Alex Alzar wrote in a statement regarding the move

IDO expressing dendritic cells suppress allograft rejection of small bowel transplantation in mice by expansion of Foxp3+ regulatory T cells