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Based on data from the literature and our preliminary study after a 4-day subacute exposure (data not shown), two exposure protocols were applied in this study for both e-cig and 3R4F emissions: a 3-month subchronic and a 6-month chronic exposure, 60 min/day and 5 days/week

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But modern cigarette smoking is a product of refinementan engineered experience designed for consistency, burn control, and maximum nicotine absorption