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Cotinine, as a metabolite of nicotine, can be detected in the body for an extended period, particularly in heavy users of nicotine products

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Thus, if a reduced nicotine content policy was adopted, supplemental use of NRT and likely other non-combustible forms of nicotine (e.g., e-cigarettes) would be a viable option for protecting against the type of performance disruptions revealed in this review, although a larger number of studies directly examining this matter would be helpful

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