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The etiology remains unknown (termed idiopathic infertility) in approximately half of infertile males with the clinical sperm profile showing oligospermia, asthenospermia, teratozoospermia, or other sperm abnormalities (Lyu et al

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Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids

The FDA has an especially critical role to play and should take several powerful actions that can accelerate progress: Implement its plan to limit nicotine in cigarettes to minimally addictive or non-addictive levels, and apply this limit to other combustible tobacco products