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Compounds at a high risk of developing drug resistance should be either refined to reduce this risk or deprioritized, whereas those with well-characterized and acceptable resistance profiles can be considered for treatment, particularly when used in combination
Also, young people, particularly young children, can have difficulty filling out questionnaires and therefore may not have provided accurate information about their early smoking behaviors
Supplementary Figure 10 Comparison of evolved TEVs with TEV mutants
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