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(In case you're wondering, here's what happens to your lungs when you give up smoking.) Ironically, however, it appears the longevity aficionado draws the line at her beloved cocktail

Although NOTCH signaling drives secretory cell fate in the differentiating airway epithelium 21,22 , and the transcription factor (TF), SPDEF 23,24 , specifically drives inflammation-induced mucus metaplasia, converting club cells into mucus cells in mice 25 , little else is known regarding regulation of human secretory cell development

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