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Recommendation 15 For people who have tried to achieve smoking cessation with first-line therapy (combination of behavioural support and TGA-approved pharmacotherapy) but failed and are still motivated to quit smoking, NVPs may be a reasonable intervention to recommend along with behavioural support

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The proportion of cancer deaths attributable to cigarette smoking varies substantially across states [but] is highest in the South, where up to 40 percent of cancer deaths in men are caused by smoking, wrote lead author and senior epidemiologist Joannie Lortet-Tieulent of the ACSs Surveillance and Health Services Research Program in Atlanta, Georgia