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The Peto method does not explicitly model age, period or cohort effects but instead captures them indirectly: age effects by computing the smoking impact ratio (SIR) within age groups (older age groups reflect longer cumulative exposure and higher lung cancer mortality risk)

Biological Mechanisms and Adolescent Vulnerability Understanding how nicotine changes the brain is key

Parental smoking cessation (quitting) and teenager substance use We examined associations between having a caregiver or caregivers who had quit smoking by Wave 2 and teenage e-cigarette use, current smoking and use of other drugs at Wave 3 aged 17/18