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Similarly, study results were generally consistent with prior PET studies of cigarette smoking and TSPO availability in people without HIV [37, 38], supporting the evidence that smoking leads to lower levels of neuroinflammation

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Of course, the association of earlier death with smoking neednt be fully causal, either: people might take up smoking as part of a generally less healthy lifestyle even if its mainly, say, their diet or a dangerous job that causes them to die sooner (they might, as implied by some research, take up smoking because theyre lonely, which complicates the situation even further)

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