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Considering the above, estimating the burden of smoking in a population can be challenging as smoking exposure can be quantified by various indicators 7,10,18,19

die each year from tobacco-related causes, according to the Centers for Disease Control and Prevention, and the move was hailed at the time as a potentially monumental public-health decision

According to the CDC, rates of e-cigarette use increased from 3.6 million in 2018 to 5.4 million in 2019 among middle and high school students

Relation of probability of causation to relative risk and doubling dose: A methodologic error that has become a social problem