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Chewing tobacco comes in the form of a loose tobacco leaf, while snuff comes in sachets similar to a tea-bag that contains dried or moist forms of finely ground tobacco [9]

Findings of our study is consistent with other data reporting the pro-inflammatory reaction and oxidative stress effects of E-smoke 4,70

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Rather, we believe that further studies in this area are needed as they may elucidate new mechanisms, perhaps involving certain components of tobacco smoke or e-cigarette vapor, that could allow for the development of novel preventative or treatment measures in the future