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Only minor dose-based differences might separate them

Because of wider NHIS-derived confidence intervals for never smokers mortality rates among people with SPD, their life expectancy estimates varied more than those of other subpopulations in sensitivity analysis

In contrast, other cells of the body suffered only indirect damage, as tobacco smoking seems to affect key mechanisms in these cells that in turn mutate DNA. Professor David Phillips An author on the paper and Professor of Environmental Carcinogenesis at Kings College London The study revealed at least five distinct processes of DNA damage due to cigarette smoking

Systematic review and meta-analysis of inhaled toxicants from waterpipe and cigarette smoking