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In particular, oral CO was shown to activate signaling cascades mediated by heme oxygenase-1 (HO-1), which plays a part in limiting oxidative stress and promoting alpha-synuclein degradation

In this country and elsewhere public health groups are working hard to limit access to [e-cigarettes], which is counterproductive to a goal of making more stop smoking treatment options available to people who smoke, said Kenneth Michael Cummings, a professor at the Medical University of South Carolina, and a vocal supporter of e-cigarettes as a cessation tool

The FDA will closely monitor how IQOS performs to ensure youth dont begin using the product

doi:10.1016/s0376-8716(99)00165-9