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Volkow and her colleagues reviewed the literature on pathophysiological processes that may hasten aging and are particularly relevant to smoking, second hand smoke, drug use, and addictions.6 They focused on oxidative stress and cellular aging, inflammation in periphery and brain, decline in brain volume and function, and early onset of cardiac, cerebrovascular, kidney, and liver disease

The next attempt, in 2012, failed even more narrowly by less than 1 percent of voters after a $48 million tobacco-funded campaign

If on electronic cigarettes we could double that or go even higher, think about the lives we'll be saving."

7 in the journal Pediatrics