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Hyperpolarized gas MRI has mainly been used as a research tool to investigate respiratory diseases including COPD (77), asthma (67), cystic fibrosis (78) and idiopathic pulmonary fibrosis (79)

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It should be noted that cigarette smoke not only affects the cardiovascular system but also has other negative effects on health, and e-cigarette aerosols contain much lower amounts of harmful and potentially harmful substances than cigarette smoke 10,25,51