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Considering the specific safety concerns, contraindications (for example, bupropion is contraindicated in patients who have seizures) and comorbidities, the choice of agent is based largely on patient preference after discussion with a clinician [footnote 53]

Members of OSH published their analyses in the CDCs Morbidity and Mortality Weekly Report (MMWR), a critical instrument for communicating epidemiological data in the U.S