The antihistamines and cold medicines can contribute to addiction if taken in large quantities or more often than prescribed
Serum Concentrations of Cotinine and Trans-3-Hydroxycotinine in US Adults: Results From Wave 1 (20132014) of the Population Assessment of Tobacco and Health Study Connie Sosnoff, Kevin Caron, J Akins, Kristin Dortch, Ronald Hunter, Brittany Pine, June Feng, Benjamin Blount, Yao Li, Bemmel van, Heather Kimmel, Kathryn Edwards, Maciej Goniewicz, Dorothy Hatsukami, Castro de, John Bernert, Stephen Arnstein, Nicolette Borek, Ying Deng-Bryant, Elena Mishina, Charles Lawrence, Andrew Hyland, Stephen Hecht, Kevin Conway, James Pirkle, Lanqing Wang Nicotine & Tobacco Research 7
This translates to difficulty keeping up with the group, needing more rest breaks, and potentially even being forced to abandon the trek due to exhaustion
Bulmer, R