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To those who want to reduce the harm connected to their use of nicotine, there are now a range of safer options available, including nicotine vapes (e-cigarettes), heated tobacco products, nicotine pouches, snus and nicotine replacement therapy

The levels of cotinine reported in our study align with the results of a previous study that evaluated nicotine and cotinine levels in the Jordanian population, which reported that the average plasma cotinine level in smokers and non-smokers was 379.4 ng/mL and 50 ng/mL, respectively 15