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Lately, as also noted by the American Heart Association statement [211], hookah has been considered a global threatin partdue to the high increase of its use, in addition to the deleterious effects it has on human body such as frequent respiratory infections, persistent cough, oral and esophageal cancer, and induction of a pro-inflammatory state

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Until now, tobacco products such as e-cigarettes have been regulated by a patchwork of state and local laws, says Andy Tan, PhD, MPH, MBA, MBBS, a cancer communication researcher at Dana-Farber