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The active ingredient in marijuana, THC, interferes with the brains endocannabinoid system, which can change how the brain and reproductive organs communicate

49 In another study, adolescent conduct problems predicted nicotine dependence after two years, with greater effects for males than for females, although other baseline factors such as parental nicotine dependence and adolescent smoking levels were of greater influence

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What is Virginia's cigarette tax compared to DC and Maryland