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The guidance creates the threat that the FDA will authorize particular flavors as lower risk based on a snapshot of flavor preferences at one point in time, only to have the authorized flavor increase in youth prevalence, the groups added

Nicotine patches giving off a steady, low amount of nicotine are preferred to nicotine gums which create higher fluctuation in nicotine levels

The American College of Obstetrics and Gynecology recommends that these products be used in pregnancy only when non-drug methods such as counseling have failed, and when the increased chance of quitting smoking with these products outweighs the unknown risks of nicotine use during pregnancy