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Also, there is the possibility that the patients in the index study may represent a self-selected sample, which may not be representative of all COPD smokers

Some vape devices offer nicotine-free options, while others use nicotine salts with concentrations as high as 50 mg/mL, particularly in pod systems and disposable vapes

United States: 20 cigarettes per pack standard European Union: 20 cigarettes minimum required Canada: 20-25 cigarettes typical pack sizes Australia: 20-25 cigarettes standard sizes Japan: 20 cigarettes standard pack size Furthermore, most countries adopted 20-cigarette minimum standards

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