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There are multiple studies that support the association between specific genetic variations and the development of addiction, according to a 2022 article by Alhammad et al., published in the journal Cureus , titled Family, Individual, and Other Risk Factors Contributing to Risk of Substance Abuse in Young Adults: A Narrative Review. According to the authors, variations in the brain-derived neurotrophic factor (BDNF) gene, OPRM1 , OPRD1 , and OPRK1 are associated with increased vulnerability to addiction

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