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Excessive vaping has been reported to induce inflammatory responses including mitogen-activated protein kinase, Janus tyrosine kinase/signal transducer and activator of transcription and nuclear factor-B signaling, similar to that induced by tobacco smoke

111-31 (2009) (Tobacco Control Act or TCA), was intended to provide a pathway for new tobacco products to reach the market, the fact that so few have been authorized by FDA is itself evidence that the premarket process is flawed