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As urine contains quantitatively significant NNK metabolites, the NNAL levels in urine are critically useful in studies of human exposure to tobacco smoke

Residual nicotine from tobacco smoke that is absorbed by indoor surfaces like upholstery, clothing and even wallpaper can react with a common indoor pollutant, ambient nitrous acid, to form hazardous carcinogenic tobacco-specific nitrosamines (TSNAs), says a study published in the Proceedings of the National Academy of Sceinces (PNAs)

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