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Patients have fever, malaise, myalgia and arthralgia Painful / tender erythema with local erosions and blisters quickly progress to areas of confluent erythema with sheet-like skin and mucosal loss Mucosal involvement includes the eyes, lips / mouth, oesophagus, upper respiratory tract, and genitalia and gastrointestinal tract resulting in diarrhoea Refer to the notes in the section below on mucosal surfaces Subcorneal pustular dermatosis (figure 33) The usual distribution is the flexural areas of the trunk and proximal extremities Lesions arise as numerous small, sterile pustules