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It can lead to further problems like irregular periods, or completely missing the period cycle for more than weeks," Dr Soumya Shetty added.
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In addition, avoiding direct comparison between the harms of traditional cigarettes and ENDS is recommended due to existing uncertainties, in particular those related to the high prevalence of dual or multiple product use, the variability of types/generations of ENDS and in their levels of nicotine content, and to a lack of rigourous and standardised comparative studies
Among the 36 smokingoutcome pairs analyzed, smoking fracture was the only binary riskoutcome pair, which was due to limited data on the doseresponse risk of smoking on fracture 202
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