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According to Cleveland, common pancreatic cancer symptoms include: Jaundice or a yellowing of the skin Dark urine Light-colored stool Stomach pain Pain in the middle of the back Fatigue Itchy skin Nausea and vomiting Gas or bloating Lack of appetite Blood clots Weight loss New-onset diabetes First symptoms of pancreatic cancer The above symptoms tend to occur in later stages of the disease, and there are "no tell-tale signs" of early pancreatic cancer, but some patients will develop "vague" symptoms up to a year before they get diagnosed, per Cleveland Clinic

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EZH2 and H3K27me3 expression was higher, while DAB2IP was lower levels, in bronchial epithelium from COPD and Smokers than in Controls