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1 Introduction Allergic diseases (AD) are a global public health problem and, according to experts from the World Allergy Organization, the number of patients with allergic diseases increases by 50% every 10 years (Pawankar et al., 2008) and by 2050 about 4 billion people will suffer from allergy ( The mechanism of sensitization and development of allergic inflammation is a consequence of the interaction of a large number of molecular factors with allergens that differ in structure and often are acting in a complex with high- and low-molecular compounds, representatives of the microbial community, as well as under the influence of external environment

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