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Sources suggest that nicotine pouches are viewed internally as having lower technological and intellectual property risks compared to heated tobacco products, which remain unapproved for domestic sale

Once we had estimated the age attenuation factors, we carried out the last step, which consisted of adjusting the risk curve for the reference age group from step 1 using equation (1) to produce the age group-specific risk curves for each CVD outcome: We implemented the age adjustment at the draw level so that the uncertainty of the age attenuation factors could be naturally incorporated into the final adjusted age-specific RR curves

c Sex-specific smokeless tobacco consumers were 33% and 23% for females and males, respectively (n=872)

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