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We assessed endothelial function with FMD, a validated measure of cardiovascular health effects2427 that has been used by numerous groups to evaluate cardiovascular effects of smoke exposure in humans and animals.2831 3436 Therefore, our approach provides a robust readout of potential adverse effects of IQOS aerosol on endothelial function, and indicates that IQOS use is likely to have rapid adverse vascular effects comparable with those from cigarette smoking

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According to the American Cancer Society, clove cigarettes have the same health concerns as regular cigarettes, including an increased risk of cancer and heart disease