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Problems arise when the LES weakens or relaxes too oftenthis is where stomach acid finds a way to rise and irritate the esophagus

Yet such single cigarettes also come with pitfalls

Health warnings The pack must carry a health warning covering 30% of the surfaces of the unit packet and any outside packaging stating This product contains nicotine which is a highly addictive substance. The Medicines and Healthcare products Regulatory Agency (MHRA) is the competent authority for the notification scheme for e-cigarettes and refill containers in the UK.[27] Consumers and healthcare professionals can report side effects and safety concerns with e-cigarettes or refill containers to the MHRA through the Yellow Card reporting system.[28] They can also report products suspected to be defective or non-compliant to their local Trading Standards service or to [email protected]

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