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Diagnoses of lung cancer were based on the best evidence available, about 70% were from biopsy, autopsy, or sputum cytology (combined with bronchoscopy or X-ray evidence), 29% were from cytology, bronchoscopy, or X-ray alone and only 1% were from just case history, physical examination, or death certificate

Two main signatures were observed under PG/VG plus nicotine conditions, T cell exhaustion and increased inflammation, both of which exacerbate cancer progression

Funding and promoting educational campaigns about tobacco use, information, and proven resources to help people quit tobacco use

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