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Since its inception, CI-BD has achieved remarkable success, with full production capabilities, in less than a decade

Chan between 2016 and 2017 by indirect immunofluorescence at a 1:80 dilution using the NOVA Lite HEp-2 ANA slide with DAPI kit (Inova Diagnostics, San Diego, California, USA), with a highly specific fluorescein isothiocyanate-conjugated secondary antibody (goat anti-human IgG)

Neutrophils are the primary source of two tissue-damaging factors myeloperoxidase and neutrophil elastase