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Interestingly, mitochondria have their own genome (mitochondrial DNA (mtDNA)) and mtDNA gene expression changes have been identified in smokers: a comparative analysis showed that 32 out of 37 mitochondrial genes were upregulated in smokers with normal lung function, nine of which were shared in vapers, indicating an important involvement of mitochondrial genes in the cellular response to smoking [33]

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2 Adjusting Strategies and Celebrating Milestones Based on your observations, modify your plan to address challenges and reinforce successful tactics

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