Indeed also in IBD, current smoking was associated with poor adherence to oral aminosalicylate therapy in a Korean study (OR of 4.1), nonadherence to anti-TNF therapies (both infliximab and adalimumab) in another study, and higher rates of nonadherence to (any) medications in women with IBD during pregnancy was demonstrated in smokers in the study by Nielsen et al [72-74]
While the 20 different Zyn products authorized for marketing and sale in the US received FDA authorization for marketing as a modified risk tobacco product (MRTP) in June 2026, they are only allowed to make the specific claim that, Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema, and chronic bronchitis. No other oral nicotine product has been granted an MRTP order
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