RESEARCH PAPER Oral squamous cell carcinoma: Effect of tobacco and alcohol on cancer location More details Hide details 1 Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki University Hospital, Helsinki, Finland 2 Department of Oral and Maxillofacial Diseases, Kymenlaakso Central Hospital Kotka, Kotka, Finland 3 Translational Immunology Research Program (TRIMM), University of Helsinki, Helsinki, Finland 4 Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland 5 Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland 6 Department of Pathology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland 7 Department of Oral Medicine and Diagnostic Sciences, King Saud University College of Dentistry, Riyadh, Saudi Arabia Submission date: 2023-12-07 Final revision date: 2024-05-12 Acceptance date: 2024-05-25 Publication date: 2024-06-18 Corresponding author Riikka Eloranta Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, FI-00029 HUS, Finland Tob
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This involves the increased production of reactive oxygen species (ROS) and a concomitant impairment of antioxidant defenses, such as glutathione [6, 7]
Although these effects are short-lived, theyre already sufficient for those seeking to overcome a sad or stressful day
