use of e cigarettes Notes from the Field: Electronic and Any Tobacco Product Among Middle and High School Students — United States, 2011–2018 About E-Cigarettes (Vapes) | Smoking

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People with the following conditions should speak with a healthcare professional before using nicotine products: High blood pressure (hypertension) Heart disease Previous heart attack Stroke history Irregular heartbeat Pregnancy Nicotine may complicate cardiovascular management, particularly when blood pressure is already difficult to control

Nevertheless, how long cotinine, nicotine for that matter, depends on the way/method and how often you ingest it

Food intake : Eating beforehand may soften the initial sensation