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TNF, which can be elevated in COPD, significantly increased the expression of intercellular adhesion molecules VCAM1, ICAM1, and E-selectin as well as the cytokines CCL2 (C-C motif ligand 2) and CX3CL1 (C-X3-C motif chemokine ligand 1) [136]

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Matthew Myers, who recently retired as president of advocacy group Campaign for Tobacco-Free Kids, said the government's failure to enforce the law is allowing companies like Heaven Gifts to make "massive profits," while putting "anybody who tries to do the right thing" at a disadvantage