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Figure 1 and Supplementary Table S1 show that exclusive HTP users had modestly but significantly lower HDL-C concentrations than never smokers, with a pooled mean difference of 1.1 (95% CI 1.5 to 0.6) mg/dL

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Brazil and the Netherlands are seeing success after they implemented MPOWER tobacco control measures, with Brazil making a relative reduction of 35% since 2010 and the Netherlands on the verge of reaching the 30% target The consistent decline in tobacco consumption across developed economies presents a significant challenge for the global tobacco industry, as evidenced by record-low smoking rates in countries such as the U.S., UK, Japan, and the Netherlands