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A study conducted in China found that 62.5% of university students who currently use e-cigarettes believed these products to be less addictive than conventional cigarettes, thereby augmenting their inclination toward using e-cigarettes 14

At any rate, considering that the main objective of any treatment for patients with CS is to reestablish normal function of the nasosinusal mucosa and the evidence that cigarette smoking impairs mucociliary transport, reducing cilia beat, the ciliogenesis or epithelial regeneration process, a proper education for these patients towards interrupting cigarette smoking as well as reinforcing campaigns against smoking are extremely important to control this disease that has a major socio-economic impact

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Mouse models have also confirmed that e-cigarettes increase immune cells like macrophages and neutrophils, as well as multiple COPD-related cytokines, including CCL2, IL-4, IL-13, IL-10, M-CSF, and TNF-