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Varenicline is not suitable for everyone, including people who: have a history of mental health conditions are pregnant or nursing have severe kidney conditions have a history of seizures or other neurological conditions take certain medications, including anticonvulsants, antibiotics, and antidepressants In June 2021, Pfizer halted production of Chantix due to the presence of high levels of nitrosamines

Although some travelers may mistakenly believe that vaping is allowed on airplanes, most airlines explicitly prohibit using e-cigarettes and other similar devices on board due to concerns about fire hazards and potential disruption to other passengers

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