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Current smoking (defined as a survey participant smoking at least once a month and having smoked more than 100 cigarettes in their lifetime) prevalence was 8.3% (95% CI: 7.7-9.0%), which is approximately 362,000 adults (see Appendix, Figure A1)

Moreover, dynamic multi-omics profiling that couples microbial composition with host immune and metabolic states will be pivotal to identifying keystone species and functional nodes amenable to therapeutic manipulation

These hormones increase lipolysis, subsequently increasing free fatty acid release and impairing endothelial function, which may contribute to insulin resistance 12