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Once stuck in the pleura, these fibers cause: Chronic inflammation Genetic mutations (changes) Production of abnormal cellular proteins Free radical (oxidation) damage to the tissue A 2018 study published in Frontiers in Immunology details how asbestos fibers alter immune function

In this Perspective, we describe the distribution and chemical changes that occur as SHS is transformed into THS, studies of environmental contamination by THS, human exposure studies, toxicology studies using animal models and in vitro systems, possible approaches for avoiding exposure, remediation of THS contamination, and priorities for further research

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