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Funding This project was financially supported by the National Natural Science Foundation of China (31571983, 31701767, 31960532), and Program for Innovative Research Team (in Science and Technology) in University of Yunnan Province (Yunjiaoke 201422)

FAILURE TO DISCLOSE OR ADEQUATELY DISCLOSE THE SMOKING POLICY OR CHANGES TO THE SMOKING POLICY The DOL reserves the right to reject offering plans and amendments thereto that fail to comply with this guidance document and all other applicable laws and regulations

Based on a 85% retention, we expect an effective sample size to be between 1199 (design effect of 1.29 or ICC of 0.01) and 631 (design effect of 2.45 or ICC of 0.05)

The film was a commercial success, grossing over $215 million worldwide